The 75 year-old Seneca is located on a charming tree-lined residential street that's only steps to the east of Michigan Avenue. The hotel features brilliant chandeliers, artfully arched doorways, handsome inlaid carpeting, and rich furnishings. The 'round-the-clock staff prides itself in greeting residents by name. A doorman is on hand to assist in any way. A valet shop and a full service beauty salon are located on the arcade level. Enjoy a deli and two restaurants without leaving the building. There are three meeting rooms and a business center on site. Valet parking is available for about 30. There is also an outdoor sunroof and a 24-hour fitness facility at this hotel.

Seneca enjoys an elite Chicago location within walking distance of the children's museum at Navy Pier, ESPN Zone, the historic Water Tower, Rush Street, and Marshall Field. American Girl Place, Lake Michigan Oak Street Beach, Loyola University, and Navy North Pier are a mile away. Chicago Loop Business Center and McCormic Convention Center are two miles away, Comiskey Park is seven miles away, and Sears Tower, Symphony Center, and Union Station are three miles from the hotel.